PUBLICATIONS

  

Kwasna D, Abdul Rehman SA, Natarajan J, Matthews S, Madden R, De Cesare V, Weidlich S, Virdee S, Ahel I, Gibbs-Seymour I* and Kulathu Y*. (2018) Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Molecular Cell.

Pubmed


Schuller M, Mautner K, Gibbs-Seymour I, Uth K, Sieg C, Gehring AP, Ahel I, Bracher F, Kessler BM, Elkins JM, Knapp S. (2017) Discovery of a selective macrodomain inhibitor targeting PARP14 macrodomain 2. ACS Chemical Biology.

Pubmed

Bonfiglio JJ, Fontana P, Zhang Q, Colby T, Gibbs-Seymour I, Atanassov I, Bartlett E, Zaja R, Ahel I, Matic I. (2017) Serine ADP-ribosylation depends on HPF1. Molecular Cell.

Pubmed

Staples CJ, Barone G, Myers KN, Ganesh A, Gibbs-Seymour I, Patil AA, Beveridge RD, Daye C, Beniston R, Maslen S, Ahel I, Skehel JM, Collis SJ. (2016) MRNIP/C5orf45 interacts with the MRN complex and contributes to the DNA damage response. Cell Reports.

Pubmed

Gibbs-Seymour I, Fontana P, Rack JG, Ahel I. (2016) HPF1/C4orf27 is a PARP-1 interacting protein that regulates PARP-1 activity. Molecular Cell.

Pubmed

Gibbs-Seymour I, Oka Y, Rajendra E, Weinert B, Passmore L, Patel K J, Olsen J V, Choudary C, Bekker-Jensen S, Mailand N. (2015) Ubiquitin-SUMO circuitry controls activated Fanconi Anemia ID complex dosage at sites of DNA damage. Molecular Cell.

Pubmed

Gibbs-Seymour I, Mailand N. (2015) SLX4: Not SIMply a nuclease scaffold? Molecular Cell.

Pubmed

Gibbs-Seymour I, Markiewicz E, Bekker-Jensen S, Mailand N, Hutchison C. (2015) Lamin A/C-dependent interaction with 53BP1 promote cellular responses to DNA damage. Aging Cell.

Pubmed

Mailand N*, Gibbs-Seymour I*, Bekker-Jensen S*. (2013) Regulation of PCNA-protein interactions for genome stability. Nature Reviews Molecular Cell Biology.

Pubmed

Mosbech A*, Gibbs-Seymour I*, Kagias K, Thorslund T, Beli P, Povlsen L, Nielsen SV, Smedegaard S, Sedgwick G, Lukas C, Hartmann-Petersen R, Lukas J, Choudhary C, Pocock R, Bekker-Jensen S, Mailand N. (2012) DVC1/C1orf124 is a DNA damage-targeting VCP/p97 adaptor that promotes ubiquitin dependent responses to replication blocks. Nature Structural and Molecular Biology

Recommended on Faculty of 1000   

Pubmed

Pekovic V*, Gibbs-Seymour I*, Markiewicz E, Alzoghaibi F, Benham AM, Edwards R, Wenhert M, von Zglinicki T, Hutchison CJ. (2011) Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation. Aging Cell.

Pubmed
 

(* joint first authorship)